Patients with epilepsy who had amnestic mild cognitive impairment (aMCI) or Alzheimer disease (AD) presented earlier with cognitive decline than patients who did not have epilepsy, according to a report published by JAMA Neurology.
AD increases a patient’s risk of risk of seizures, and patients with AD and seizure disorders have greater cognitive impairment, more rapid progression of symptoms and more severe neuronal loss at autopsy than those without seizures, according to the study background.